SCHEMBL1743988

SCHEMBL1743988

Nc1c([N+](=O)[O-])cc([N+](=O)[O-])c(O)c1CCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 5/20 0.45
CA9 Q16790 4/20 0.41
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NSD2 O96028 1/20 0.41
GAA P10253 1/20 0.41
PLCG1 P19174 1/20 0.41
DNMT1 P26358 1/20 0.41
CASP6 P55212 1/20 0.41
ALDH1A1 P00352 4/20 0.40
ALOX15 P16050 2/20 0.40
MAPK1 P28482 2/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
CYP1A2 P05177 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27752557 0.87 GPR35 (0.45) GPR35CA9CA12CA1CA2
SCHEMBL20873532 0.80 KAT2B (0.53) L3MBTL1GAAALDH1A1MEN1MAPT
SCHEMBL28424080 0.78 GPR35 (0.44) GPR35CA9CA12CA1CA2
SCHEMBL16863642 0.73 TSHR (0.40) L3MBTL1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL17867141 0.73 GPR35 (0.53) GPR35CA9CA12CA1CA2
SCHEMBL1758269 0.73 GPR35 (0.52) GPR35CA9CA12CA1CA2
SCHEMBL10716436 0.73 ALDH1A1 (0.43) GPR35ALDH1A1ALOX15MAPK1KDM4E
SCHEMBL9479697 0.72 SNCA (0.39) GPR35CA9CA12CA1CA2
SCHEMBL2882236 0.72 ALDH1A1 (0.42) GPR35ALDH1A1MAPK1MEN1MAPT
SCHEMBL28271658 0.72 ALDH1A1 (0.44) GPR35ALDH1A1MAPK1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025061335-A1 METHOD FOR DYEING KERATIN FIBRES, COMPRISING THE APPLICATION OF AN OXIDATIVE PRE-TREATMENT AGENT AND A DYE COMPRISING DIRECT DYES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
WO-2021121823-A1 TINTING CONDITIONER HAVING IMPROVED DYEING PERFORMANCE HENKEL AG & CO. KGAA (DE) 2021-06-24 WO claimed
EP-3723864-A1 THICKENED ONE-COMPONENT HAIR TONER Henkel AG & Co. KGaA (DE) 2020-10-21 EP claimed
EP-2012742-B1 BLEACHING AND/OR COLOURING AGENTS CONTAINING PIPERIDONES HENKEL AG & CO KGAA (DE) 2014-03-19 EP claimed
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP claimed
EP-0608393-B1 HAIR DYES WELLA AG (DE) 1996-03-20 EP claimed
EP-0600045-B1 HAIR DYE WELLA AG (DE) 1996-01-24 EP claimed
WO-2025072691-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR HART TAYLOR (US) 2025-04-03 WO disclosed
US-20250107976-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2025-04-03 US disclosed
US-20250107975-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2025-04-03 US disclosed
WO-2025061335-A1 METHOD FOR DYEING KERATIN FIBRES, COMPRISING THE APPLICATION OF AN OXIDATIVE PRE-TREATMENT AGENT AND A DYE COMPRISING DIRECT DYES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO disclosed
EP-4496557-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED COMPLEXING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP disclosed
CN-113677318-B Increasing the stability of agents for treating keratin materials 汉高股份有限及两合公司 2024-07-09 CN disclosed
US-8041873-B2 Multiple module computer system and method including differential signal channel comprising unidirectional serial bit channels to transmit encoded peripheral component interconnect bus transaction data ACQIS LLC (US) 2011-10-18 US disclosed
EP-2345400-A2 Lightening composition having reduced hair damage Henkel AG & Co. KGaA (DE) 2011-07-20 EP disclosed
EP-2320868-A2 HAIR PREPARATION COMPRISING SPIRULINA EXTRACT Henkel AG & Co. KGaA (DE) 2011-05-18 EP disclosed
WO-2010029005-A2 HAIR PREPARATION COMPRISING SPIRULINA EXTRACT HENKEL AG & CO. KGAA (DE) 2010-03-18 WO disclosed
EP-2075036-A1 Disulfid dyes, composition comprising them and method of dyeing hair Ciba Holding Inc. (CH) 2009-07-01 EP disclosed
EP-1750663-A2 DISULFIDE DYES, COMPOSITION COMPRISING THEM AND METHOD OF DYEING HAIR CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-02-14 EP disclosed
WO-2005097051-A2 DISULFIDE DYES, COMPOSITION COMPRISING THEM AND METHOD OF DYEING HAIR CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-10-20 WO disclosed