Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271658 | 0.87 | ALDH1A1 (0.44) | ALDH1A1CYP3A4VCAM1MAPTUSP7 | |
| SCHEMBL7643608 | 0.80 | TSHR (0.46) | ALDH1A1CYP3A4VCAM1MAPTUSP7 | |
| SCHEMBL198863 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP3A4VCAM1MAPTUSP7 | |
| SCHEMBL27752557 | 0.79 | GPR35 (0.45) | ALDH1A1MAPTGPR35MEN1KMT2A | |
| SCHEMBL8108409 | 0.78 | ALDH1A1 (0.39) | ALDH1A1CYP3A4VCAM1MAPTUSP7 | |
| SCHEMBL4592068 | 0.77 | POLB (0.44) | ALDH1A1CYP3A4VCAM1MAPTPDE7A | |
| SCHEMBL9650502 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CYP3A4VCAM1MAPTUSP7 | |
| SCHEMBL5484250 | 0.73 | TSHR (0.44) | ALDH1A1CYP3A4MAPTGPR35MEN1 | |
| SCHEMBL1743988 | 0.72 | GPR35 (0.45) | ALDH1A1CYP3A4MAPTGPR35MEN1 | |
| SCHEMBL5352319 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP3A4VCAM1MAPTUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233854-B1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING A PYRAZOLOPYRIDINE UNIT | OREAL (FR) | 2018-11-21 | — | — | EP | disclosed |
| CN-106924056-A | For the make-up composition of keratin fiber | 莱雅公司 | 2017-07-07 | — | — | CN | disclosed |
| EP-2170260-A1 | AZO DERIVATIVES CONTAINING A PYRAZOLINONE UNIT FOR DYEING KERATIN FIBRES | L'Oreal (FR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009000753-A1 | AZO DERIVATIVES CONTAINING A PYRAZOLINONE UNIT FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 2008-12-31 | — | — | WO | disclosed |