SCHEMBL17440168

SCHEMBL17440168

CCCCCOO[Si](=O)O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 5/20 0.39
LPAR2 Q9HBW0 4/20 0.39
LPAR1 Q92633 2/20 0.39
NAAA Q02083 1/20 0.39
CES2 O00748 1/20 0.38
EPHX1 P07099 1/20 0.36
CA1 P00915 6/20 0.35
CA2 P00918 6/20 0.35
CA9 Q16790 6/20 0.35
MEN1 O00255 1/20 0.35
THRB P10828 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
CA12 O43570 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17440167 0.81 CA1 (0.38) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL2537730 0.74 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL1157409 0.74 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL1276156 0.74 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL543796 0.74 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL76192 0.74 LPAR3 (0.45) LPAR3LPAR2LPAR1NAAACES2
Ammonia Solution, Strong SCHEMBL4405541 0.74 LPAR3 (0.40) LPAR3LPAR2LPAR1NAAACES2
SCHEMBL170225 0.72
SCHEMBL28285588 0.71 THRB (0.50) LPAR3LPAR2LPAR1NAAACA1
SCHEMBL30094 0.71 THRB (0.50) LPAR3LPAR2LPAR1NAAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016011032-A1 SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2016-01-21 WO disclosed