Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406201 | 0.75 | LTA4H (0.36) | NISCH | |
| SCHEMBL14372921 | 0.68 | PKM (0.36) | NISCH | |
| SCHEMBL7765721 | 0.66 | HRH3 (0.34) | NISCH | |
| SCHEMBL3652062 | 0.62 | CA2 (0.31) | — | |
| SCHEMBL10687434 | 0.62 | P2RX4 (0.33) | NPC1RAB9A | |
| SCHEMBL446185 | 0.61 | ABCG2 (0.36) | NISCH | |
| SCHEMBL353825 | 0.61 | PARP1 (0.40) | NISCH | |
| SCHEMBL1107770 | 0.61 | POLB (0.43) | NISCH | |
| SCHEMBL8525523 | 0.61 | POLB (0.43) | NISCH | |
| SCHEMBL11404710 | 0.61 | CA2 (0.41) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385934-A1 | INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3) AND INDUCERS OF NITRIC OXIDE (NO) | Council of Scientific & Industrial Research (IN) | 2011-11-16 | — | — | EP | disclosed |
| US-8041964-B2 | Ultra low power wake-up circuit | COVIDIEN AG (CH) | 2011-10-18 | — | — | US | disclosed |