Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921375 | 0.68 | EPHX2 (0.44) | L3MBTL1EPHX2HSD17B10EPHX1HSD11B1 | |
| SCHEMBL6154505 | 0.65 | EPHX2 (0.58) | L3MBTL1EPHX2HSD17B10EPHX1HSD11B1 | |
| SCHEMBL9115097 | 0.62 | EPHX2 (0.54) | L3MBTL1EPHX2HSD17B10EPHX1HSD11B1 | |
| SCHEMBL13702321 | 0.61 | L3MBTL1 (0.72) | L3MBTL1EPHX2NPSR1HSD17B10HSD11B1 | |
| SCHEMBL12968364 | 0.61 | L3MBTL1 (0.72) | L3MBTL1EPHX2NPSR1HSD17B10HSD11B1 | |
| SCHEMBL6154544 | 0.61 | EPHX2 (0.41) | L3MBTL1EPHX2HSD17B10HSD11B1 | |
| SCHEMBL11150613 | 0.60 | L3MBTL1 (0.41) | L3MBTL1EPHX2NPSR1USP2 | |
| Hydrochloric Acid SCHEMBL9115349 | 0.60 | SIGMAR1 (0.55) | L3MBTL1EPHX2HSD17B10EPHX1HSD11B1 | |
| SCHEMBL3353684 | 0.59 | — | — | |
| SCHEMBL944590 | 0.59 | EPHX2 (0.41) | L3MBTL1EPHX2HSD17B10EPHX1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386547-A1 | Multicyclic amino acid derivatives and methods of their use | Lexicon Pharmaceuticals, Inc. (US) | 2011-11-16 | — | — | EP | disclosed |
| US-8039086-B2 | Bonding material, process for producing the same, and honeycomb structure made with the same | NGK INSULATORS, LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2011100285-A1 | TRYPTOPHAN HYDROXYLASE INHIBITORS FOR THE TREATMENT OF METASTATIC BONE DISEASE | LEXICON PHARMACEUTICALS, INC. (US) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011056916-A1 | TRYPTOPHAN HYDROXYLASE INHIBITORS FOR THE TREATMENT OF CANCER | LEXICON PHARMACEUTICALS, INC. (US) | 2011-05-12 | — | — | WO | disclosed |