Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | PRKCA | P17252 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960608 | 0.95 | ALDH1A1 (0.71) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL28537632 | 0.95 | ALDH1A1 (0.71) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL7053932 | 0.95 | ALDH1A1 (0.71) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL18960823 | 0.95 | ALDH1A1 (0.71) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL18960607 | 0.95 | ALDH1A1 (0.71) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL28528192 | 0.95 | ALDH1A1 (0.71) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL18960824 | 0.95 | ALDH1A1 (0.71) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| Ethyl Oleate SCHEMBL6369771 | 0.93 | ALOX15 (0.69) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| Ethyl Oleate SCHEMBL6369777 | 0.93 | ALOX15 (0.69) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL25490302 | 0.93 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169317-B1 | OXYMORPHONE TRANSDERMAL PATCH | BUZZZ PHARMACEUTICALS LTD (IE) | 2020-04-08 | — | — | EP | disclosed |
| EP-3169318-B1 | ABUSE DETERRENT OPIOD/OPIOD-ANTAGONIST TRANSDERMAL PATCH | BUZZZ PHARMACEUTICALS LTD (IE) | 2020-04-01 | — | — | EP | disclosed |
| US-10238648-B2 | Abuse deterrent opioid/opioid-antagonist transdermal patch | BUZZZ PHARMACEUTICALS LTD. (IE) | 2019-03-26 | — | — | US | disclosed |
| US-10071090-B2 | Oxymorphone transdermal patch | BUZZZ PHARMACEUTICALS LIMITED (IE) | 2018-09-11 | — | — | US | disclosed |
| US-20170209429-A1 | ABUSE DETERRENT OPIOD/OPIOD-ANTAGONIST TRANSDERMAL PATCH | BUZZZ PHARMACEUTICALS LIMITED (IE) | 2017-07-27 | — | — | US | disclosed |
| US-20170202830-A1 | OXYMORPHONE TRANSDERMAL PATCH | BUZZZ PHARMACEUTICALS LIMITED (IE) | 2017-07-20 | — | — | US | disclosed |
| EP-3169317-A1 | OXYMORPHONE TRANSDERMAL PATCH | Buzzz Pharmaceuticals Limited (IE) | 2017-05-24 | — | — | EP | disclosed |
| EP-3169318-A1 | ABUSE DETERRENT OPIOD/OPIOD-ANTAGONIST TRANSDERMAL PATCH | Buzzz Pharmaceuticals Limited (IE) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016009063-A1 | OXYMORPHONE TRANSDERMAL PATCH | BUZZZ PHARMACEUTICALS LIMITED (IE) | 2016-01-21 | — | — | WO | disclosed |
| WO-2016009064-A1 | ABUSE DETERRENT OPIOD/OPIOD-ANTAGONIST TRANSDERMAL PATCH | BUZZZ PHARMACEUTICALS LIMITED (IE) | 2016-01-21 | — | — | WO | disclosed |