Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541688 | 0.86 | CYP2D6 (0.74) | CYP2D6DRD3SLC6A2HRH1CHRM2 | |
| SCHEMBL29907915 | 0.86 | CYP2D6 (0.74) | CYP2D6DRD3SLC6A2HRH1CHRM2 | |
| SCHEMBL19179335 | 0.82 | PGR (0.51) | CNR2FABP4FABP5 | |
| SCHEMBL6219453 | 0.79 | CYP2D6 (0.65) | CYP2D6DRD3SLC6A2HRH1CHRM2 | |
| SCHEMBL10702688 | 0.77 | SLC6A4 (0.64) | CYP2D6DRD3SLC6A2HRH1CHRM2 | |
| SCHEMBL9776455 | 0.77 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL11826363 | 0.76 | CYP2D6 (0.59) | CYP2D6DRD3SLC6A2HRH1CHRM2 | |
| SCHEMBL975310 | 0.75 | PGR (0.44) | CNR2ALDH1A1 | |
| Fantridone SCHEMBL1683047 | 0.75 | PGR (0.69) | CYP2D6DRD3SLC6A2HRH1CHRM2 | |
| SCHEMBL11142970 | 0.75 | PGR (0.56) | CNR2ALDH1A1FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016008010-A1 | FUNCTIONALISED AND SUBSTITUTED CARBAZOLES AS ANTI-CANCER AGENTS | Novogen ltd (AU) | 2016-01-21 | — | — | WO | disclosed |