SCHEMBL975310

SCHEMBL975310

CCCCn1c2c[c]ccc2c2cc[c]cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 4/20 0.44
RORA P35398 4/20 0.44
RORC P51449 4/20 0.44
RORB Q92753 4/20 0.44
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 4/20 0.36
TSHR P16473 1/20 0.36
TLR8 Q9NR97 1/20 0.36
PSEN1 P49768 2/20 0.35
PSEN2 P49810 2/20 0.35
APH1B Q8WW43 2/20 0.35
NCSTN Q92542 2/20 0.35
APH1A Q96BI3 2/20 0.35
PSENEN Q9NZ42 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6420678 0.93 PSEN1 (0.43) PGRRORARORCRORBTLR8
SCHEMBL6420677 0.93 PSEN1 (0.43) PGRRORARORCRORBTLR8
SCHEMBL6423058 0.93 PSEN1 (0.43) PGRRORARORCRORBTLR8
SCHEMBL973713 0.89 HPGD (0.37) PGRRORARORCRORBTDP1
SCHEMBL19179335 0.87 PGR (0.51) PGRRORARORCRORBPSEN1
SCHEMBL974629 0.85 PGR (0.44) PGRRORARORCRORBTDP1
SCHEMBL11142970 0.82 PGR (0.56) PGRRORARORCRORBTDP1
SCHEMBL976299 0.80 ALDH1A1 (0.39) TDP1L3MBTL1ALDH1A1TSHRKDM4E
SCHEMBL14976913 0.77 PGR (0.51) PGRRORARORCRORBPSEN1
SCHEMBL6418678 0.76 ALDH1A1 (0.38) TDP1ALDH1A1TSHRKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475937-B2 Silicone composition and organic light-emitting diode DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
EP-2262861-B1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING (US) 2012-09-19 EP disclosed
US-20110017986-A1 Silicone Composition and Organic Light-Emitting Diode DOW CORNING CORPORATION 2011-01-27 US disclosed
EP-2262861-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE Dow Corning Corporation (US) 2010-12-22 EP disclosed
WO-2009120434-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING CORPORATION (US) 2009-10-01 WO disclosed