Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1089020 | 0.84 | ALDH1A1 (0.51) | TDP1ALDH1A1TSHRHTTMAOB | |
| SCHEMBL3843256 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1TSHRHTTMAOB | |
| SCHEMBL10694908 | 0.81 | ALDH1A1 (0.39) | TDP1ALDH1A1TSHRHTTMAOB | |
| SCHEMBL28901826 | 0.81 | ALDH1A1 (0.46) | TDP1ALDH1A1TSHRHTTMAOB | |
| SCHEMBL5711756 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1TSHRHTTMEN1 | |
| SCHEMBL24707429 | 0.78 | AKR1B1 (0.39) | ALDH1A1MAOBLMNA | |
| SCHEMBL12648507 | 0.77 | TDP1 (0.50) | TDP1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22499465 | 0.77 | TDP1 (0.40) | TDP1ALDH1A1TSHRHTTMAOB | |
| SCHEMBL20096043 | 0.75 | KAT6A (0.35) | TDP1ALDH1A1CA2MMP1MMP2 | |
| SCHEMBL30273921 | 0.75 | ALDH1A1 (0.43) | TDP1ALDH1A1TSHRCA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016906-A1 | SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT | AMGEN INC. (US) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016906-A1 | SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT | SI, AREG, CA12 | TDP1 4129/4885ALDH1A1 2291/4885TSHR 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.