SCHEMBL17445478

SCHEMBL17445478

c1ccc(-c2cc(-n3c4ccccc4c4c5c(c6ccccc6c43)c3ccccc3c3c5c4ccccc4n3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 2/20 0.38
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
NTSR1 P30989 1/20 0.35
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
GLA P06280 1/20 0.34
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK1 P28482 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17445367 0.90 L3MBTL1 (0.42) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL17445362 0.90 L3MBTL1 (0.42) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17445479 0.89 KMT2A (0.47) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17445389 0.89 MAPT (0.34) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL12131874 0.88 MEN1 (0.41) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17445480 0.88 KMT2A (0.44) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17445340 0.88 L3MBTL1 (0.40) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL19046676 0.87 ACHE (0.36) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17123113 0.87 L3MBTL1 (0.44) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL26473109 0.87 MEN1 (0.37) MEN1KMT2AHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9780314-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-10-03 US disclosed
US-9780314-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-10-03 US disclosed
US-20160020408-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-21 US disclosed
US-20160020408-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160020408-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF OR51E2, NFE2L2, ORAI2 MEN1 1254/4885KMT2A 569/4885HPGD 3085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.