Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 10/20 | 0.35 |
| ▸ | CA1 | P00915 | 9/20 | 0.35 |
| ▸ | CA9 | Q16790 | 8/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18104322 | 0.92 | ADRB2 (0.32) | CA2CA1 | |
| SCHEMBL18776469 | 0.90 | SPHK1 (0.31) | SPHK1CA2CA1CA9CA12 | |
| SCHEMBL17445657 | 0.90 | LPAR2 (0.41) | — | |
| SCHEMBL12731238 | 0.83 | HSD17B10 (0.30) | — | |
| SCHEMBL15624011 | 0.82 | LMNA (0.30) | TSHRMEN1KMT2A | |
| SCHEMBL21178108 | 0.82 | SPHK1 (0.37) | SPHK1CA2CA1CA9CA12 | |
| SCHEMBL22801258 | 0.82 | SPHK1 (0.37) | SPHK1CA2CA1CA9CA12 | |
| SCHEMBL20709888 | 0.82 | SPHK1 (0.37) | SPHK1CA2CA1CA9CA12 | |
| SCHEMBL21178019 | 0.82 | SPHK1 (0.37) | SPHK1CA2CA1CA9CA12 | |
| SCHEMBL18817977 | 0.82 | SPHK1 (0.37) | SPHK1CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803198-B2 | Lipohillic oligonucleotide analogs | MILTENYI BIOTEC, GMBH (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20160017325-A1 | LIPOHILLIC OLIGONUCLEOTIDE ANALOGS | MILTENYI BIOTEC GMBH (DE) | 2016-01-21 | — | — | US | disclosed |