Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516720 | 0.91 | CYP1A2 (0.62) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL5111673 | 0.87 | LMNA (0.74) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL9471057 | 0.87 | LMNA (0.74) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL1746424 | 0.86 | FFAR1 (0.62) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL19479625 | 0.84 | CYP1A2 (0.68) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL11730903 | 0.83 | L3MBTL1 (0.68) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL28165618 | 0.82 | MAOB (0.60) | PKMLMNAL3MBTL1NR4A2PPARG | |
| SCHEMBL27566556 | 0.80 | LMNA (0.60) | FFAR1AKR1B1FFAR4LMNAL3MBTL1 | |
| SCHEMBL10500644 | 0.80 | CYP1A2 (0.74) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL7976627 | 0.80 | CYP1A2 (1.00) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |