Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | PPARG | P37231 | 5/20 | 0.66 |
| ▸ | PPARA | Q07869 | 5/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471057 | 1.00 | LMNA (0.74) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL11730903 | 0.95 | L3MBTL1 (0.68) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL10732880 | 0.89 | LMNA (0.72) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL10867537 | 0.88 | LMNA (0.70) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL28724154 | 0.88 | LMNA (0.70) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL28165618 | 0.88 | MAOB (0.60) | LMNAL3MBTL1PPARGPPARAPKM | |
| SCHEMBL1744700 | 0.87 | CYP1A2 (0.64) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL27516720 | 0.86 | CYP1A2 (0.62) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL1746424 | 0.86 | FFAR1 (0.62) | LMNAL3MBTL1PPARGPPARACYP1A2 | |
| SCHEMBL11008605 | 0.86 | NR4A2 (0.61) | LMNAL3MBTL1PPARGPPARAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547582-A | Method of producing herbicide intermediates | STAUFFER CHEMICAL COMPANY (US) | 1985-10-15 | — | — | US | claimed |
| EP-2310371-B1 | PPAR AGONIST COMPOUNDS AND PREPARATION AND USES THEREOF FOR TREATING DIABETES AND/OR DYSLIPIDEMIA | GENFIT (FR) | 2013-05-15 | — | — | EP | disclosed |
| US-20080146631-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | BROOKS DAWN ALISA | 2008-06-19 | — | — | US | disclosed |
| US-7351728-B2 | Oxazolyl-aryloxyacetic acid derivatives and their use as PPAR agonists | ELI LILLY AND COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1313715-B1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | LILLY CO ELI (US) | 2007-08-01 | — | — | EP | disclosed |
| US-6982278-B2 | Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists | ELI LILLY AND COMPANY (US) | 2006-01-03 | — | — | US | disclosed |
| US-20050250825-A1 | Oxazolyl-aryloxyacetic acid derivatives and their use as PPAR agonists | BROOKS DAWN A | 2005-11-10 | — | — | US | disclosed |
| US-20040024034-A1 | Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists | BROOKS DAWN ALISA (US) | 2004-02-05 | — | — | US | disclosed |
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-1994013647-A1 | (2-QUINOXALINYLOXY)PHENOXYPROPANOIC ACIDS AND RELATED DERIVATIVES AS ANTICANCER AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-06-23 | — | — | WO | disclosed |
| WO-1994000532-A1 | 1-METHYL-2-OXAALKOXY-DERIVATIVES | MERCK PATENT GMBH (DE) | 1994-01-06 | — | — | WO | disclosed |
| EP-0121871-B1 | PROPIONIC-ACID ESTERS AND THEIR USE IN COMBATING WEEDS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-01-20 | — | — | EP | disclosed |
| EP-0178054-A2 | Herbicide intermediates and production thereof | STAUFFER CHEMICAL COMPANY (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4547582-A | Method of producing herbicide intermediates | STAUFFER CHEMICAL COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| US-4547582-A | Method of producing herbicide intermediates | STAUFFER CHEMICAL COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| US-4540804-A | Herbicide intermediates | STAUFFER CHEMICAL COMPANY (US) | 1985-09-10 | — | — | US | disclosed |
| US-4537984-A | Process for producing 2-(4-hydroxyphenoxy) propionate derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-08-27 | — | — | US | disclosed |
| EP-0129034-A1 | process for producing 2-(4-hydroxyphenoxy) propionate derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1984-12-27 | — | — | EP | disclosed |
| EP-0121871-A1 | Propionic-acid esters and their use in combating weeds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250825-A1 | Oxazolyl-aryloxyacetic acid derivatives and their use as PPAR agonists | PPARA, PPARG, PPARD | LMNA 3367/4885L3MBTL1 3955/4885PPARG 2/4885 |
| US-20040024034-A1 | Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists | PPARA, PPARG, PPARD | LMNA 3537/4885L3MBTL1 3347/4885PPARG 2/4885 |
| US-20080146631-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | PPARA, PPARG, PPARD | LMNA 1860/4885L3MBTL1 3714/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.