SCHEMBL1744703

SCHEMBL1744703

O=C(O)CCc1ccc(OCCc2cccc3ccccc23)cc1

nearest known ligand 0.79

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 18/20 0.79
AKR1B1 P15121 3/20 0.79
FFAR4 Q5NUL3 6/20 0.56
LMNA P02545 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1746720 0.88 FFAR1 (1.00) FFAR1AKR1B1FFAR4
SCHEMBL3954071 0.88 FFAR1 (0.61) FFAR1AKR1B1L3MBTL1
SCHEMBL1745296 0.86 FFAR1 (0.59) FFAR1AKR1B1L3MBTL1
SCHEMBL6378589 0.86 FFAR1 (0.58) FFAR1AKR1B1
SCHEMBL1745370 0.81 FFAR1 (1.00) FFAR1AKR1B1FFAR4LMNAL3MBTL1
SCHEMBL8358132 0.81 KCNA3 (0.59) FFAR1AKR1B1L3MBTL1
SCHEMBL29930767 0.81 FFAR1 (0.59) FFAR1AKR1B1FFAR4LMNAL3MBTL1
SCHEMBL1218835 0.80 TDP1 (0.67) FFAR1AKR1B1FFAR4
SCHEMBL30307853 0.80 TDP1 (0.67) FFAR1AKR1B1FFAR4
SCHEMBL6385594 0.79 PPARG (0.65) FFAR1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1559422-B1 RECEPTOR FUNCTION CONTROLLING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-04-30 EP disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR FFAR1 33/4885AKR1B1 1186/4885FFAR4 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.