SCHEMBL1746720

SCHEMBL1746720

O=C(O)CCc1ccc(OCc2cccc3ccccc23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 1.00
AKR1B1 P15121 1/20 1.00
FFAR4 Q5NUL3 13/20 0.67
PARP10 Q53GL7 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1744703 0.88 FFAR1 (0.79) FFAR1AKR1B1FFAR4
SCHEMBL25034484 0.86 FFAR1 (0.76) FFAR1AKR1B1FFAR4PARP10
SCHEMBL30874126 0.86 FFAR1 (0.76) FFAR1AKR1B1FFAR4PARP10
SCHEMBL1744466 0.86 FFAR1 (0.75) FFAR1AKR1B1FFAR4PARP10
SCHEMBL10689361 0.81 FFAR1 (0.71) FFAR1AKR1B1FFAR4
SCHEMBL28570332 0.81 FFAR1 (0.71) FFAR1AKR1B1FFAR4
SCHEMBL1745273 0.81 FFAR1 (0.73) FFAR1AKR1B1FFAR4
SCHEMBL2350889 0.81 FFAR1 (0.67) FFAR1AKR1B1FFAR4PARP10
SCHEMBL10349749 0.81 PARP10 (0.71) FFAR1AKR1B1PARP10
SCHEMBL4058335 0.80 PARP10 (0.76) FFAR1AKR1B1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1559422-B1 RECEPTOR FUNCTION CONTROLLING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-04-30 EP disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
CN-1735408-A Receptor function controlling agent TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2006-02-15 CN disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR FFAR1 33/4885AKR1B1 1186/4885FFAR4 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.