Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19154684 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL20975935 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL1753752 | 0.82 | MEN1 (0.51) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL17448211 | 0.82 | EPHX1 (0.43) | NPC1LMNANAMPTMAPT | |
| SCHEMBL17448208 | 0.81 | LTA4H (0.47) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL25457857 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL19370640 | 0.77 | CTSB (0.38) | SMN1; SMN2MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL19592560 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL21671263 | 0.77 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2ARAB9AHPGD | |
| SCHEMBL19491612 | 0.77 | KMT2A (0.58) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280229-B2 | Linkers and their application towards ADC | MEDSHINE DISCOVERY INC. (CN) | 2019-05-07 | — | — | US | disclosed |
| US-20170202974-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | MEDSHINE DISCOVERY INC. (CN) | 2017-07-20 | — | — | US | disclosed |
| WO-2016008392-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | MEDSHINE DISCOVERY INC. (CN) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202974-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | DNPEP, DPP7, DPP3 | SMN1; SMN2 2988/4885L3MBTL1 1457/4885MEN1 3002/4885 |
| US-10280229-B2 | Linkers and their application towards ADC | DNPEP, DPP7, DPP3 | SMN1; SMN2 2988/4885L3MBTL1 1457/4885MEN1 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.