Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420627 | 0.74 | THRB (0.41) | THRBMEN1KMT2A | |
| SCHEMBL22597833 | 0.68 | — | — | |
| SCHEMBL22330751 | 0.67 | LMNA (0.30) | — | |
| SCHEMBL17324149 | 0.67 | LMNA (0.30) | — | |
| SCHEMBL4466587 | 0.65 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL10274596 | 0.64 | THRB (0.91) | THRBMEN1KMT2A | |
| SCHEMBL21651619 | 0.64 | THRB (0.91) | THRBMEN1KMT2A | |
| SCHEMBL8965981 | 0.64 | THRB (0.91) | THRBMEN1KMT2A | |
| SCHEMBL743465 | 0.64 | THRB (0.91) | THRBMEN1KMT2A | |
| SCHEMBL9909392 | 0.64 | THRB (0.91) | THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016010897-A1 | BICYCLIC HETEROAROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2016-01-21 | — | — | WO | disclosed |