SCHEMBL4466587

SCHEMBL4466587

NC1CCC2(N)CCCCC12

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11420627 0.91 THRB (0.41) THRBMEN1KMT2A
SCHEMBL20124566 0.67
SCHEMBL18306055 0.66 KDM4E (0.35)
SCHEMBL6429936 0.66 KDM4E (0.35)
SCHEMBL17448657 0.65 THRB (0.39) THRBMEN1KMT2A
SCHEMBL13513582 0.65 KDM4E (0.32)
SCHEMBL11274052 0.64 ALDH1A1 (0.41)
SCHEMBL23740127 0.64 KDM4E (0.34)
SCHEMBL8777072 0.64 KDM4E (0.34)
SCHEMBL20104757 0.64 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1801163-B1 Siloxane Encapsulants ROHM & HAAS (US) 2009-08-05 EP disclosed
US-20070148476-A1 Siloxane encapsulants KHANARIAN GARO 2007-06-28 US disclosed
EP-1801163-A1 Siloxane Encapsulants Rohm and Haas Company (US) 2007-06-27 EP disclosed
US-20060134440-A1 Silicone encapsulants for light emitting diodes ENERGY, UNITED STATES DEPARTMENT OF 2006-06-22 US disclosed
EP-1652871-A1 Silicone encapsulants for light emitting diodes RENSSELAER POLYTECHNIC INSTITUTE (US) 2006-05-03 EP disclosed