SCHEMBL17449196

SCHEMBL17449196

Cc1sc(C)c2c1OCCOCCOCCOCCOc1ccccc1OCCOCCOCCOCCO2

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
CRHBP P24387 2/20 0.63
CRHR2 Q13324 2/20 0.63
HTT P42858 2/20 0.63
ITGB2 P05107 1/20 0.52
ICAM1 P05362 1/20 0.52
ITGAL P20701 1/20 0.52
GAA P10253 2/20 0.51
KDM4E B2RXH2 3/20 0.45
MAPT P10636 5/20 0.39
BLM P54132 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
KMT2A Q03164 1/20 0.36
ADRB1 P08588 1/20 0.36
CD274 Q9NZQ7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15981866 0.84 LMNA (0.33) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL15981883 0.84 LMNA (0.33) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL17449209 0.84 LMNA (0.33) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505395 0.79 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL35679 0.79 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL23658043 0.79 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL676131 0.79 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL603441 0.79 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL8026205 0.79 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505745 0.79 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10950811-B2 Optoelectronic component HELIATEK GMBH (DE) 2021-03-16 US disclosed
EP-2959520-B1 OPTOELECTRONIC COMPONENT HELIATEK GMBH (DE) 2017-02-01 EP disclosed
US-20160020419-A1 OPTOELECTRONIC COMPONENT HELIATEK GMBH (DE) 2016-01-21 US disclosed
US-20160020419-A1 OPTOELECTRONIC COMPONENT HELIATEK GMBH (DE) 2016-01-21 US disclosed