Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.61 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449234 | 1.00 | S1PR2 (0.61) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| Bromide SCHEMBL14060445 | 0.98 | S1PR2 (0.59) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| Bromide SCHEMBL14060814 | 0.98 | S1PR2 (0.59) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL17577720 | 0.86 | S1PR2 (0.45) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL2941289 | 0.82 | PPARD (0.54) | PPARD | |
| SCHEMBL2185289 | 0.82 | PPARD (0.54) | PPARD | |
| SCHEMBL3980817 | 0.82 | PPARD (0.54) | PPARD | |
| SCHEMBL503890 | 0.82 | PPARD (0.54) | PPARD | |
| SCHEMBL503511 | 0.82 | PPARD (0.54) | PPARD | |
| SCHEMBL8029516 | 0.82 | PPARD (0.54) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850265-B2 | Amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use | GRI BIO, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160016981-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | GLYCOREGIMMUNE, INC. (US) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016981-A1 | AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE | AADAT, AASDHPPT, ASS1 | S1PR2 1701/4885S1PR1 1696/4885S1PR3 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.