Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557681 | 0.91 | HDAC1 (0.44) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL26091795 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL26091800 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL26091793 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL4087824 | 0.84 | ITGB3 (0.38) | ITGB3ITGA2BHDAC8PARP12 | |
| SCHEMBL30930695 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL29261147 | 0.82 | ITGB3 (0.41) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL29261148 | 0.82 | ITGB3 (0.41) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL29261151 | 0.82 | ITGB3 (0.41) | ITGB3ITGA2BHDAC1HDAC2HDAC3 | |
| SCHEMBL2927304 | 0.82 | CNR2 (0.39) | ITGB3ITGA2BHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386572-B1 | Insulin derivative | NOVO NORDISK AS (DK) | 2015-07-08 | — | — | EP | disclosed |
| US-8933021-B2 | Insulin derivative | NOVO NORDISK A/S (DK) | 2015-01-13 | — | — | US | disclosed |
| EP-2386572-A1 | Insulin derivative | Novo Nordisk A/S (DK) | 2011-11-16 | — | — | EP | disclosed |
| US-8039101-B2 | Radio-opaque dental prosthetic member | Societe de Recherches Techniques Dentaires-R.T.D. (FR) | 2011-10-18 | — | — | US | disclosed |
| US-20090239785-A1 | Insulin Derivative | NOVO NORDISK A/S (DK) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239785-A1 | Insulin Derivative | IAPP, INSR, GPR119 | ITGB3 4146/4885ITGA2B 4474/4885HDAC1 3452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.