Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071201 | 0.73 | MAOA (0.45) | KMT2APOLBALDH1A1LMNAL3MBTL1 | |
| Bromide SCHEMBL6061518 | 0.71 | MAOA (0.44) | KMT2APOLBALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6061385 | 0.71 | MAOA (0.47) | KMT2APOLBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7300273 | 0.70 | ALDH1A1 (0.53) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL5914768 | 0.69 | MEN1 (0.43) | MEN1KMT2ANPC1ALDH1A1GAA | |
| SCHEMBL11453734 | 0.67 | MAPT (0.43) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL7666503 | 0.67 | SMN1; SMN2 (0.58) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL7843193 | 0.66 | L3MBTL1 (0.40) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL29586112 | 0.65 | ALDH1A1 (0.60) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL5454000 | 0.64 | ALDH1A1 (0.61) | MEN1KMT2APOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016010610-A2 | IMIDAZOLE AND THIAZOLE COMPOSITIONS FOR MODIFYING BIOLOGICAL SIGNALING | OHIO UNIVERSITY (US) | 2016-01-21 | — | — | WO | disclosed |