Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357083 | 0.77 | KDM4E (0.40) | KDM4EHTTL3MBTL1MAPTMAPK1 | |
| SCHEMBL2306361 | 0.77 | KDM4E (0.40) | KDM4EHTTL3MBTL1MAPTMAPK1 | |
| SCHEMBL3751398 | 0.77 | KDM4E (0.40) | KDM4EHTTL3MBTL1MAPTMAPK1 | |
| SCHEMBL3344886 | 0.73 | ALDH1A1 (0.31) | KDM4EHTTL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL3069796 | 0.72 | KDM4E (0.38) | KDM4EHTTMAPTHSD17B10ALDH1A1 | |
| SCHEMBL3066491 | 0.72 | KDM4E (0.36) | KDM4EHTTMAPTHSD17B10ALDH1A1 | |
| SCHEMBL5014297 | 0.72 | KDM4E (0.36) | KDM4EHTTL3MBTL1MAPTALDH1A1 | |
| SCHEMBL2309750 | 0.72 | TSHR (0.38) | KDM4EHTTMAPTHSD17B10ALDH1A1 | |
| SCHEMBL2309754 | 0.71 | KDM4E (0.36) | KDM4EHTTMAPTHSD17B10ALDH1A1 | |
| SCHEMBL3701209 | 0.71 | KDM4E (0.36) | KDM4EHTTMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350077-B1 | FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | ENTASIS THERAPEUTICS LTD (GB) | 2016-01-27 | — | — | EP | disclosed |