Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | METAP2 | P50579 | 8/20 | 0.39 |
| ▸ | METAP1 | P53582 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CAD | P27708 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251996 | 1.00 | MGAM (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL805100 | 0.81 | — | — | |
| SCHEMBL864303 | 0.81 | — | — | |
| SCHEMBL804999 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL4589404 | 0.79 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15156949 | 0.79 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL31252142 | 0.78 | MGAM (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL23264148 | 0.78 | — | — | |
| SCHEMBL11185813 | 0.78 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5814208 | 0.77 | METAP2 (0.46) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239755-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-07-18 | — | — | US | disclosed |
| CN-107531673-B | Herbicidal compounds | 先正达参股股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| US-9944608-B2 | Herbicidal pyridazinone derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-20170166535-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-15 | — | — | US | disclosed |
| WO-2016008816-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239755-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | PNPO, WEE1, PDXK | MGAM 461/4885GAA 1104/4885SI 2746/4885 |
| US-20170166535-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | HPD, DDT, PDXK | MGAM 662/4885GAA 426/4885SI 3292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.