Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | TTR | P02766 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888226 | 0.89 | BACE1 (0.59) | BACE1MAPTALDH1A1MEN1KMT2A | |
| Methyl 3-(2,4-Dichlorophenyl)Acrylate SCHEMBL6315070 | 0.85 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3532294 | 0.85 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| Methyl 3-(2,4-Dichlorophenyl)Acrylate SCHEMBL7434845 | 0.85 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3532296 | 0.85 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14926720 | 0.84 | MAPT (0.50) | BACE1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7573821 | 0.83 | ALDH1A1 (0.76) | BACE1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29886427 | 0.83 | ALDH1A1 (0.76) | BACE1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29372443 | 0.83 | BACE1 (0.63) | BACE1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28754820 | 0.83 | BACE1 (0.63) | BACE1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |
| CN-1735408-A | Receptor function controlling agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-15 | — | — | CN | disclosed |