SCHEMBL1745518

SCHEMBL1745518

CCN(Cc1ccc(COc2ccc(CCC(=O)O)cc2)cc1)c1ccccc1C

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 18/20 0.61
FFAR4 Q5NUL3 6/20 0.61
L3MBTL1 Q9Y468 1/20 0.52
TSPO P30536 1/20 0.52
AKR1B1 P15121 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1746717 0.83 FFAR1 (0.61) FFAR1FFAR4TSPOAKR1B1
SCHEMBL1747380 0.83 FFAR1 (0.58) FFAR1FFAR4L3MBTL1TSPOAKR1B1
SCHEMBL1746786 0.82 FFAR1 (0.63) FFAR1FFAR4AKR1B1
SCHEMBL1745516 0.82 FFAR1 (0.76) FFAR1FFAR4AKR1B1
SCHEMBL1745418 0.82 FFAR1 (0.64) FFAR1FFAR4L3MBTL1AKR1B1
SCHEMBL1746820 0.81 L3MBTL1 (0.78) FFAR1FFAR4L3MBTL1AKR1B1
SCHEMBL1746738 0.80 FFAR1 (0.61) FFAR1FFAR4L3MBTL1AKR1B1
SCHEMBL19266669 0.80 FFAR1 (0.68) FFAR1FFAR4L3MBTL1AKR1B1
SCHEMBL1747255 0.79 FFAR1 (0.60) FFAR1FFAR4L3MBTL1AKR1B1
SCHEMBL1746788 0.79 FFAR1 (0.70) FFAR1FFAR4AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1559422-B1 RECEPTOR FUNCTION CONTROLLING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-04-30 EP disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR FFAR1 33/4885FFAR4 44/4885L3MBTL1 4392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.