SCHEMBL1745539

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1747068	0.92	FFAR1 (0.43)	FFAR1LMNAL3MBTL1MAPTHRH3
	SCHEMBL1747248	0.90	GRIN2B (0.44)	FFAR1MAPTKMT2APPARDALDH1A1
	SCHEMBL15679161	0.89	HRH3 (0.40)	FFAR1HRH3KMT2APPARDALDH1A1
	SCHEMBL1746586	0.89	FFAR1 (0.46)	FFAR1PPARDFFAR4PPARA
	SCHEMBL1746743	0.88	KDM5A (0.40)	FFAR1SLC6A4HRH3KMT2A
	SCHEMBL1744781	0.88	FFAR4 (0.44)	FFAR1SLC6A4HRH3ADRB2ADRB1
	SCHEMBL1744547	0.88	IDO1 (0.41)	FFAR1SLC6A4HRH3ADRB2ADRB1
	SCHEMBL1747100	0.86	FFAR1 (0.45)	FFAR1MAPTHRH3KMT2AALDH1A1
	SCHEMBL1744689	0.86	FFAR1 (0.46)	FFAR1PPARDPPARA
	SCHEMBL1745269	0.85	KMT2A (0.46)	KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.