SCHEMBL1746743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1744691	0.92	HRH3 (0.42)	FFAR1KMT2AATMHRH3MEN1
	SCHEMBL1747248	0.89	GRIN2B (0.44)	FFAR1KMT2AMEN1CCR2
	SCHEMBL1745539	0.88	FFAR1 (0.40)	FFAR1KMT2ASLC6A4HRH3
	SCHEMBL1745475	0.88	FFAR1 (0.50)	KDM5AKDM4CKDM5BFFAR1SLC6A4
	SCHEMBL1744781	0.87	FFAR4 (0.44)	KDM5AKDM4CKDM5BFFAR1SLC6A4
	SCHEMBL1744547	0.87	IDO1 (0.41)	FFAR1SLC6A4HRH3CCR2
	SCHEMBL1746551	0.87	KDM5A (0.41)	KDM5AKDM4CKDM5BFFAR1SLC6A4
	SCHEMBL1744565	0.85	TRPV1 (0.42)	KDM5AKDM4CKDM5BFFAR1KMT2A
	SCHEMBL15679161	0.85	HRH3 (0.40)	FFAR1KMT2AHRH3MEN1
	SCHEMBL1747100	0.85	FFAR1 (0.45)	FFAR1KMT2AHRH3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.