Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319961 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2PIK3CDPIK3CGCCNA2CDK2 | |
| SCHEMBL17675158 | 0.73 | CA1 (0.41) | SMN1; SMN2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL27174917 | 0.73 | PHGDH (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL1094850 | 0.72 | PIK3CD (0.33) | SLC1A3SLC1A2SLC1A1PIK3CDPIK3CA | |
| SCHEMBL21695368 | 0.64 | GRM5 (0.45) | SMN1; SMN2 | |
| SCHEMBL326998 | 0.64 | PIK3CD (0.33) | GRM4SMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL20557467 | 0.63 | CDK5 (0.34) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL20557462 | 0.63 | CDK5 (0.43) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL16094686 | 0.63 | ALPL (0.35) | — | |
| SCHEMBL27851069 | 0.62 | HSD17B10 (0.47) | SMN1; SMN2PIK3CGCCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385938-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited (GB) | 2011-11-16 | — | — | EP | disclosed |
| US-8040476-B2 | Display device and method of producing the same | MITSUBISHI ELECTRIC CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010079443-A1 | SULFONAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-07-15 | — | — | WO | disclosed |