Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19246202 | 1.00 | MEN1 (0.65) | MEN1CYP1A2KMT2A | |
| SCHEMBL7099701 | 1.00 | MEN1 (0.65) | MEN1CYP1A2KMT2A | |
| SCHEMBL21880677 | 0.92 | MEN1 (0.58) | MEN1KMT2A | |
| SCHEMBL12150096 | 0.92 | MEN1 (0.60) | MEN1CYP1A2KMT2A | |
| SCHEMBL12318199 | 0.92 | MEN1 (0.60) | MEN1CYP1A2KMT2A | |
| SCHEMBL12270468 | 0.92 | MEN1 (0.58) | MEN1KMT2A | |
| SCHEMBL12150142 | 0.92 | MEN1 (0.60) | MEN1CYP1A2KMT2A | |
| SCHEMBL16579926 | 0.90 | — | — | |
| SCHEMBL12318387 | 0.90 | — | — | |
| SCHEMBL19518941 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411390-A1 | MODULATION OF BACTERIAL QUORUM SENSING WITH SYNTHETIC LIGANDS | WISCONSIN ALUMNI RES FOUND (US) | 2022-12-29 | — | — | US | disclosed |
| US-20200115356-A1 | Modulation of Bacterial Quorum Sensing With Synthetic Ligands | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2020-04-16 | — | — | US | disclosed |
| US-9796694-B2 | Modulation of bacterial quorum sensing with synthetic ligands | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-17 | — | — | US | disclosed |
| WO-2016013844-A1 | PRODUCTION METHOD OF PHENYLACETYL HOMOSERINE LACTONE DERIVATIVE | 한국생명공학연구원 | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | PNISR, PGLS, QRFPR | MEN1 3990/4885CYP1A2 4846/4885KMT2A 3286/4885 |
| US-20200115356-A1 | Modulation of Bacterial Quorum Sensing With Synthetic Ligands | AHCYL1, EBPL, AIP | MEN1 4259/4885CYP1A2 3568/4885KMT2A 2147/4885 |
| US-20220411390-A1 | MODULATION OF BACTERIAL QUORUM SENSING WITH SYNTHETIC LIGANDS | AHCYL1, EBPL, AIP | MEN1 4259/4885CYP1A2 3568/4885KMT2A 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.