Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600603 | 0.97 | DNM1 (0.62) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| SCHEMBL7297733 | 0.97 | DNM1 (0.62) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| SCHEMBL1686201 | 0.95 | DNM1 (0.57) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| Water SCHEMBL3307120 | 0.92 | DNM1 (0.55) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| SCHEMBL28463174 | 0.89 | DNM1 (0.50) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| SCHEMBL28461185 | 0.89 | DNM1 (0.50) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| Bromide SCHEMBL7214859 | 0.89 | DNM1 (0.55) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| Bromide SCHEMBL5936903 | 0.87 | DNM1 (0.61) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| Water SCHEMBL3305378 | 0.86 | DNM1 (0.48) | DNM1ALDH1A1TSHRHSD17B10TP53 | |
| Water SCHEMBL3302989 | 0.86 | DNM1 (0.48) | DNM1ALDH1A1TSHRHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016013001-A2 | AN \"ON-DEMAND\" SELF-DEGRADING POLYMER COMPOSITION AND METHOD THEREOF | TAMA PLASTIC INDUSTRY (IL) | 2016-01-28 | — | — | WO | disclosed |