Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272419 | 0.97 | DNM1 (0.52) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| Iodide SCHEMBL14777716 | 0.94 | DNM1 (0.50) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL14734829 | 0.94 | DNM1 (0.50) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| Water SCHEMBL319990 | 0.94 | DNM1 (0.50) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL27408052 | 0.92 | DNM1 (0.48) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL11706247 | 0.91 | DNM1 (0.46) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| Bromide SCHEMBL17458752 | 0.89 | DNM1 (0.64) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| Water SCHEMBL3308247 | 0.88 | DNM1 (0.43) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL1686201 | 0.88 | DNM1 (0.57) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL9003642 | 0.87 | DNM1 (0.44) | DNM1ALDH1A1TSHRSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038459-A | BATTERY;WATER INSOLUBLE COMPLEX | ECO-CONTROL, INC. (US) | 1977-07-26 | — | — | US | claimed |
| CN-107151288-A | It is a kind of for flotation agent of middle matter crude oil and preparation method thereof | 天津亿利科能源科技发展股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| US-8658842-B2 | Process for producing ethylene glycol catalyzed by ionic liquid | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-25 | — | — | US | disclosed |
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2013-03-21 | — | — | US | disclosed |
| US-6616920-B1 | Copolymer of an acrylated or styrenized polysiloxane and a radical polymerizable monomer, especially an acrylic monomer containing an amine oxide or quaternium ammonium internal salt. | MITSUBISHI CHEMICAL AMERICA, INC. | 2003-09-09 | — | — | US | disclosed |
| US-5362485-A | For setting or conditioning hair; softness, luster | MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0165333-B1 | NEW COMPOUNDS CONTAINING QUATERNARY AMMONIUM AND METHYLENEPHOSPHONIC ACID GROUPS | THE DOW CHEMICAL COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4493771-A | Scale inhibiting with compounds containing quaternary ammonium and methylenephosphonic acid groups | THE DOW CHEMICAL COMPANY (US) | 1985-01-15 | — | — | US | disclosed |
| US-4459241-A | ANTIDEPOSIT AGENTS | THE DOW CHEMICAL COMPANY (US) | 1984-07-10 | — | — | US | disclosed |
| US-4147840-A | Halogen complexing homotetra-alkyl salts for use in halogen cells | ECO-CONTROL, INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4104447-A | BATTERIES | ECO-CONTROL, INC. (US) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | AGL, ALKBH3, ELL | DNM1 2294/4885ALDH1A1 1764/4885TSHR 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.