Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | HPD | P32754 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459257 | 0.79 | CHRM5 (0.40) | NOTUMTOP2APDE10ADRD2DRD3 | |
| SCHEMBL17459260 | 0.78 | CYP1A2 (0.50) | NOTUMPLA2G10 | |
| SCHEMBL28752498 | 0.74 | MGLL (0.62) | NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL29510581 | 0.74 | MGLL (0.62) | NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL11306236 | 0.73 | MAPT (0.52) | — | |
| SCHEMBL4185632 | 0.72 | PDE4B (0.48) | NOTUMTOP2APDE10AHPDPDE4B | |
| SCHEMBL10561497 | 0.70 | KAT6A (0.52) | HDAC8KAT6AHSD11B1 | |
| SCHEMBL3147185 | 0.70 | GPR3 (0.50) | — | |
| SCHEMBL3432545 | 0.70 | TDP1 (0.43) | PDE10APDE4BPDE4D | |
| SCHEMBL224912 | 0.69 | NLRP3 (0.48) | KAT6AP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963442-B2 | Pyridones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170204081-A1 | PYRIDONES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-20 | — | — | US | disclosed |
| EP-3171698-A1 | PYRIDONES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-05-31 | — | — | EP | disclosed |
| CN-106687452-A | Pyridones as herbicides | 纳幕尔杜邦公司 | 2017-05-17 | — | — | CN | disclosed |
| WO-2016014814-A1 | PYRIDONES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204081-A1 | PYRIDONES AS HERBICIDES | CYP1B1, PNPO, CYP1A1 | NOTUM 1079/4885TOP2A 500/4885PDE10A 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.