Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 14/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468345 | 0.89 | MAOB (0.42) | LTA4HSLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL17469027 | 0.89 | MAOB (0.42) | LTA4HSLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL17459287 | 0.87 | LTA4H (0.38) | LTA4HSLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL17459303 | 0.87 | LTA4H (0.38) | LTA4HSLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL17459309 | 0.87 | LTA4H (0.40) | LTA4HSLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL17459409 | 0.87 | SLC6A2 (0.40) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17459470 | 0.85 | LTA4H (0.40) | LTA4HSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL17469000 | 0.85 | MAOB (0.50) | LTA4HSLC6A4MAOBMAPT | |
| SCHEMBL17459468 | 0.85 | LTA4H (0.40) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17469164 | 0.85 | LTA4H (0.43) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |