Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 6/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468345 | 1.00 | MAOB (0.42) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL17459309 | 0.92 | LTA4H (0.40) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL17459409 | 0.89 | SLC6A2 (0.40) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17459303 | 0.89 | LTA4H (0.38) | MAOBLTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17459287 | 0.89 | LTA4H (0.38) | MAOBLTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17459277 | 0.89 | LTA4H (0.38) | MAOBKDM4ELTA4HSLC6A2SLC6A4 | |
| SCHEMBL17469146 | 0.88 | DRD3 (0.40) | LTA4HKIF11DRD3SLC6A2SLC6A4 | |
| SCHEMBL17468918 | 0.88 | LTA4H (0.38) | MAOBKDM4EHSD17B10ADORA3AR | |
| SCHEMBL17459470 | 0.87 | LTA4H (0.40) | KDM4ELTA4HALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL17459468 | 0.87 | LTA4H (0.40) | CYP19A1LTA4HDRD3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |