Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164590 | 0.83 | POLB (0.41) | CES2CES1DAOKMT2AMEN1 | |
| SCHEMBL20473166 | 0.82 | CES2 (0.38) | CES2CES1DAOKMT2AMEN1 | |
| SCHEMBL31176820 | 0.82 | CES2 (0.38) | CES2CES1DAOKMT2AMEN1 | |
| SCHEMBL4245645 | 0.81 | CES2 (0.37) | CES2CES1DAOKMT2AMEN1 | |
| SCHEMBL23326703 | 0.80 | NPSR1 (0.35) | CES2CES1DAOKMT2AMEN1 | |
| SCHEMBL16664426 | 0.80 | ALOX5 (0.44) | DAOKMT2AMEN1POLBNPSR1 | |
| SCHEMBL2481845 | 0.80 | ALOX5 (0.44) | DAOKMT2AMEN1POLBNPSR1 | |
| SCHEMBL17459402 | 0.79 | GABBR2 (0.41) | DAOKMT2AMEN1POLBWRN | |
| SCHEMBL17459279 | 0.77 | DAO (0.47) | CES2CES1DAOKMT2APOLB | |
| SCHEMBL17459305 | 0.71 | CES2 (0.38) | CES2CES1NPSR1GSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |