Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583205 | 0.77 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDGAATSHR | |
| SCHEMBL541989 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL232376 | 0.72 | ALDH1A1 (0.54) | ALDH1A1PDE4DKDM4EMEN1KMT2A | |
| SCHEMBL11583031 | 0.72 | — | — | |
| SCHEMBL22950631 | 0.70 | LMNA (0.57) | ALDH1A1KDM4EHPGDMAPK1CA2 | |
| Sulfuric Acid SCHEMBL28510110 | 0.68 | ALDH1A1 (0.49) | ALDH1A1PDE4DKDM4EMEN1KMT2A | |
| SCHEMBL7013807 | 0.67 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27824132 | 0.67 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL16852179 | 0.67 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL7822285 | 0.67 | ALDH1A1 (0.39) | ALDH1A1PDE4DKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385945-B1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER IP GMBH (DE) | 2013-01-23 | — | — | EP | disclosed |
| EP-2385945-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | Bayer Pharma Aktiengesellschaft (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-8041896-B2 | Virtualization platform with dedicated cache access | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010078953-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-15 | — | — | WO | disclosed |