SCHEMBL541989

SCHEMBL541989

Nc1n[nH]c(OC(=O)O)n1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 3/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27583205 0.82 ALDH1A1 (0.33) ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10
SCHEMBL1746012 0.74 ALDH1A1 (0.39) ALDH1A1KDM4EMEN1CYP1A2KMT2A
SCHEMBL10723126 0.71 ALDH1A1 (0.33) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL231832 0.69
SCHEMBL17548900 0.68
Water SCHEMBL2448609 0.65 CGAS (0.44) ALDH1A1KDM4EMEN1CYP1A2KMT2A
Water SCHEMBL6788837 0.65 CGAS (0.44) ALDH1A1KDM4EMEN1CYP1A2KMT2A
SCHEMBL8725835 0.64 ALDH1A1 (0.48) ALDH1A1KDM4EMEN1CYP1A2KMT2A
SCHEMBL11583031 0.64
SCHEMBL9241106 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2259665-B1 Solution for surface treatment MEC CO LTD (JP) 2012-02-08 EP claimed
EP-1310510-B1 Topologically segregated, encoded solid phase libraries AVENTIS PHARMA INC (US) 2007-07-11 EP claimed
EP-0705279-B1 TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES SELECTIDE CORP (US) 2003-02-19 EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
EP-2013144-B1 METAL OXIDES PRODUCED FROM METAL-ORGANIC FRAMEWORK MATERIALS BASF SE (DE) 2012-10-03 EP disclosed
EP-0446731-B1 Process for the manufacture of azo dyes BAYER AG (DE) 1995-05-03 EP disclosed
EP-0567849-A1 Process for preparing dyes BAYER AG (DE) 1993-11-03 EP disclosed
EP-0446731-A2 Process for the manufacture of azo dyes BAYER AG (DE) 1991-09-18 EP disclosed