SCHEMBL17460447

SCHEMBL17460447

O=C1C=Cc2ccccc2C1=NNc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 5/20 0.41
ALDH1A1 P00352 5/20 0.41
LMNA P02545 4/20 0.41
POLB P06746 3/20 0.41
PTPN1 P18031 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
BCHE P06276 1/20 0.41
PTPRC P08575 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
IDO1 P14902 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
RECQL P46063 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053808 1.00 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL17460446 1.00 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL2858004 0.93 POLB (0.46) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL21436655 0.87 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL15740338 0.87 EIF2AK2 (0.49) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL21436238 0.87 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL21055662 0.87 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL5344218 0.87 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL5344213 0.87 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL17762728 0.85 SNCA (0.41) MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172266-B1 METHOD FOR MODIFYING THE SURFACE PROPERTIES OF ELASTOMER CELLULAR FOAMS UNIV STRASBOURG (FR) 2024-07-03 EP disclosed
EP-3172266-A2 METHOD FOR MODIFYING THE SURFACE PROPERTIES OF ELASTOMER CELLULAR FOAMS Université de Strasbourg (FR) 2017-05-31 EP disclosed
WO-2016012689-A2 METHOD FOR MODIFYING THE SURFACE PROPERTIES OF ELASTOMER CELLULAR FOAMS UNIVERSITE DE STRASBOURG (FR) 2016-01-28 WO disclosed