Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436655 | 0.87 | ALDH1A1 (0.41) | EIF2AK2KMT2AMEN1POLBAPAF1 | |
| SCHEMBL21436238 | 0.87 | ALDH1A1 (0.41) | EIF2AK2KMT2AMEN1POLBAPAF1 | |
| SCHEMBL21055662 | 0.87 | ALDH1A1 (0.41) | EIF2AK2KMT2AMEN1POLBAPAF1 | |
| SCHEMBL10053808 | 0.87 | MEN1 (0.41) | EIF2AK2KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL17460446 | 0.87 | MEN1 (0.41) | EIF2AK2KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL17460447 | 0.87 | MEN1 (0.41) | EIF2AK2KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL11876526 | 0.83 | ALDH1A1 (0.49) | KMT2AMEN1POLBAPAF1CASP3 | |
| SCHEMBL333149 | 0.83 | ALDH1A1 (0.49) | KMT2AMEN1POLBAPAF1CASP3 | |
| SCHEMBL11876532 | 0.83 | ALDH1A1 (0.49) | KMT2AMEN1POLBAPAF1CASP3 | |
| SCHEMBL23960849 | 0.82 | ALDH1A1 (0.59) | KMT2AMEN1POLBTDP2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014081856-A2 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | AZZAZY HASSAN (EG) | 2014-05-30 | — | — | WO | disclosed |