Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235150 | 0.77 | ALDH1A1 (0.35) | TDP1ALDH1A1LMNA | |
| SCHEMBL14378538 | 0.75 | KDM4E (0.40) | KDM4ETDP1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11227378 | 0.73 | KDM4E (0.42) | KDM4EMEN1KMT2A | |
| SCHEMBL11220894 | 0.72 | MAPT (0.41) | ADRA1A | |
| SCHEMBL13612890 | 0.72 | LMNA (0.48) | KDM4ETDP1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL20988048 | 0.72 | LMNA (0.48) | KDM4ETDP1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL19090720 | 0.72 | LMNA (0.48) | KDM4ETDP1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7207274 | 0.71 | TSHR (0.47) | KDM4ETDP1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11232890 | 0.71 | CASR (0.36) | KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL20987984 | 0.68 | THRB (0.40) | KDM4ETDP1SMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024233-A1 | SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS | GENZYME CORPORATION | 2016-01-28 | — | — | US | disclosed |