Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17464320 | 0.81 | RET (0.38) | DUT | |
| SCHEMBL17464323 | 0.77 | NTRK1 (0.32) | — | |
| SCHEMBL15261633 | 0.75 | IRAK4 (0.42) | AXLIRAK4 | |
| SCHEMBL17464326 | 0.73 | CSNK2A1 (0.37) | IRAK4 | |
| SCHEMBL16154316 | 0.73 | DUT (0.38) | DUT | |
| SCHEMBL17441587 | 0.71 | KCNH2 (0.39) | DUT | |
| SCHEMBL15894530 | 0.70 | RET (0.35) | DUTIRAK4 | |
| SCHEMBL19252601 | 0.70 | PIM1 (0.38) | IRAK4 | |
| SCHEMBL17625382 | 0.69 | PRKAB2 (0.34) | DUT | |
| SCHEMBL4772134 | 0.69 | DUT (0.36) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024114-A1 | MACROCYCLIC RIP2 KINASE INHIBITORS | ONCODESIGN S.A. (FR) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024114-A1 | MACROCYCLIC RIP2 KINASE INHIBITORS | RIPK2, RIPK1, RIPK3 | DUT 3581/4885AXL 2956/4885IRAK4 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.