SCHEMBL17464945

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27813440	0.78	ALDH1A1 (0.37)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL10871427	0.78	TYMS (0.43)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL12590878	0.78	ALDH1A1 (0.45)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL10499821	0.78	KDM6B (0.50)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL6384356	0.78	GRIN2D (0.39)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL12820764	0.75	KDM4C (0.41)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL18336721	0.73	ALDH1A1 (0.37)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL1294842	0.73	GRIN2D (0.38)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL1187005	0.72	—	—
	SCHEMBL1163852	0.72	RECQL (0.53)	ALDH1A1TDP1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.