Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995240 | 0.80 | SLC25A5 (0.46) | BACE1L3MBTL1ALDH1A1PTPN1SLC25A5 | |
| SCHEMBL20471519 | 0.76 | BACE1 (0.37) | BACE1L3MBTL1ALDH1A1PTPN1 | |
| SCHEMBL20471518 | 0.76 | BACE1 (0.37) | BACE1L3MBTL1ALDH1A1PTPN1 | |
| SCHEMBL1414534 | 0.74 | ALDH1A1 (0.43) | BACE1L3MBTL1ALDH1A1PTPN1 | |
| SCHEMBL31603 | 0.73 | BACE1 (0.44) | BACE1ALDH1A1PTPN1 | |
| SCHEMBL4459751 | 0.72 | BACE1 (0.46) | BACE1L3MBTL1ALDH1A1PTPN1 | |
| SCHEMBL587175 | 0.72 | ALDH1A1 (0.46) | BACE1L3MBTL1ALDH1A1 | |
| SCHEMBL29663487 | 0.70 | BACE1 (0.40) | BACE1ALDH1A1PTPN1 | |
| SCHEMBL25168789 | 0.70 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1PTPN1 | |
| SCHEMBL1747216 | 0.70 | CYP2C19 (0.39) | BACE1L3MBTL1ALDH1A1PTPN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |