Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176655 | 1.00 | LMNA (0.64) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL1176657 | 1.00 | LMNA (0.64) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL17413619 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL11227796 | 0.79 | POLB (0.61) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL11227799 | 0.79 | POLB (0.61) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL20163174 | 0.79 | MAPT (0.54) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL17465992 | 0.78 | TP53 (0.62) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL30352913 | 0.78 | MAPT (0.53) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL30352917 | 0.78 | MAPT (0.53) | LMNAALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL1176560 | 0.76 | POLB (0.72) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-2888245-B1 | NEW BICYCLICPYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2016-09-21 | — | — | EP | disclosed |
| US-9410035-B2 | Modified heterophasic polyolefin composition | MILLIKEN & COMPANY (US) | 2016-08-09 | — | — | US | disclosed |
| US-9410035-B2 | Modified heterophasic polyolefin composition | MILLIKEN & COMPANY (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160024289-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY | 2016-01-28 | — | — | US | disclosed |
| US-20160024289-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY | 2016-01-28 | — | — | US | disclosed |
| WO-2016014122-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY (US) | 2016-01-28 | — | — | WO | disclosed |