SCHEMBL17465992

SCHEMBL17465992

CCCCCCCCOC(=O)/C(C#N)=C/c1ccc(C)o1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 7/20 0.62
ALDH1A1 P00352 6/20 0.55
KDM4E B2RXH2 2/20 0.55
PKM P14618 1/20 0.55
MAPT P10636 7/20 0.54
THRB P10828 1/20 0.54
LMNA P02545 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
POLB P06746 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
DNM1 Q05193 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
RXFP1 Q9HBX9 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17466000 0.93 TP53 (0.67) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL22697146 0.92 TP53 (0.63) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL22697144 0.85 TP53 (0.59) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL17465797 0.81 POLB (0.73) TP53ALDH1A1KDM4EMAPTTHRB
SCHEMBL994759 0.79 DNM1 (0.60) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL994758 0.79 DNM1 (0.60) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL1176655 0.78 LMNA (0.64) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL1176657 0.78 LMNA (0.64) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL17465993 0.78 LMNA (0.64) TP53ALDH1A1KDM4EPKMMAPT
SCHEMBL7106941 0.78 DNM1 (0.57) TP53ALDH1A1KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172272-B1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & CO (US) 2020-11-25 EP disclosed
US-9410035-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2016-08-09 US disclosed
US-9410035-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2016-08-09 US disclosed
US-20160024289-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-01-28 US disclosed
WO-2016014122-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY (US) 2016-01-28 WO disclosed
US-20160024289-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-01-28 US disclosed