SCHEMBL17467396

SCHEMBL17467396

c1cc(-c2ccc3c4ccccc4n(-c4ccc5c(c4)-c4ccccc4C5)c3c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CNR1 P21554 1/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PARP1 P09874 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
NQO1 P15559 1/20 0.32
SRD5A2 P31213 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18706718 0.94 KDM4E (0.41) KDM4EATML3MBTL1CNR1NPC1
SCHEMBL17636988 0.94 KDM4E (0.46) KDM4EATML3MBTL1NPC1ALDH1A1
SCHEMBL17467393 0.93 KDM4E (0.38) KDM4EATML3MBTL1CNR1NPC1
SCHEMBL12219167 0.91 KDM4E (0.38) KDM4EATML3MBTL1CNR1NPC1
SCHEMBL12219168 0.91 L3MBTL1 (0.43) KDM4EATML3MBTL1CNR1ALDH1A1
SCHEMBL18706529 0.91 KDM4E (0.41) KDM4EATML3MBTL1CNR1NPC1
SCHEMBL17636986 0.90 KDM4E (0.43) KDM4EATML3MBTL1NPC1ALDH1A1
SCHEMBL17636987 0.90 KDM4E (0.43) KDM4EATML3MBTL1NPC1ALDH1A1
SCHEMBL17637000 0.90 KDM4E (0.40) KDM4EATML3MBTL1CNR1NPC1
SCHEMBL12219176 0.90 L3MBTL1 (0.42) KDM4EATML3MBTL1CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 KDM4E 3396/4885ATM 2966/4885L3MBTL1 2272/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM KDM4E 4026/4885ATM 1282/4885L3MBTL1 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.