SCHEMBL17467397

SCHEMBL17467397

c1cc(-c2ccc3c4ccccc4n(-c4cccc5c4Cc4ccccc4-5)c3c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PNMT P11086 1/20 0.33
ALDH1A1 P00352 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17636994 0.94 KDM4E (0.43) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL17467402 0.93 KDM4E (0.36) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL17637021 0.91 KDM4E (0.40) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL17636990 0.91 KDM4E (0.40) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL5028290 0.91 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1
SCHEMBL17467403 0.89 KDM4E (0.37) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL18706532 0.89 KDM4E (0.35) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL18706388 0.89 KDM4E (0.35) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL15258306 0.87 KDM4E (0.43) KDM4EATML3MBTL1PNMTALDH1A1
SCHEMBL17636989 0.87 KDM4E (0.43) KDM4EATML3MBTL1PNMTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 KDM4E 3396/4885ATM 2966/4885L3MBTL1 2272/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM KDM4E 4026/4885ATM 1282/4885L3MBTL1 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.