SCHEMBL5028290

SCHEMBL5028290

c1cc(-c2ccc3c(c2)-c2cccc(-n4c5ccccc5c5ccccc54)c2C3)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 1/20 0.31
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17467402 0.91 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1
SCHEMBL17467397 0.91 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1
SCHEMBL17052840 0.90 EDNRB (0.33) KDM4EATML3MBTL1ALDH1A1
SCHEMBL25751809 0.89 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1
SCHEMBL29343586 0.87 L3MBTL1 (0.46) KDM4EATML3MBTL1ALDH1A1PDE10A
SCHEMBL19333111 0.86 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL26531296 0.85 PNMT (0.35) KDM4EALDH1A1
SCHEMBL19333128 0.85 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL12219168 0.84 L3MBTL1 (0.43) KDM4EATML3MBTL1ALDH1A1PDE10A
SCHEMBL17636994 0.84 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed