Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721916 | 0.83 | PARP1 (0.39) | CHRM1DRD3SLC6A9 | |
| SCHEMBL28722176 | 0.83 | PARP1 (0.39) | CHRM1DRD3SLC6A9 | |
| SCHEMBL23860097 | 0.81 | DRD3 (0.36) | CHRM1DRD3SLC6A9SIGMAR1 | |
| SCHEMBL1499106 | 0.79 | GPR119 (0.41) | — | |
| SCHEMBL17467697 | 0.77 | DRD3 (0.40) | CHRM1DRD3SLC6A9SIGMAR1 | |
| SCHEMBL28719989 | 0.77 | CHRM1 (0.42) | CHRM1DRD3SLC6A9SIGMAR1 | |
| SCHEMBL28719987 | 0.77 | CHRM1 (0.42) | CHRM1DRD3SLC6A9SIGMAR1 | |
| SCHEMBL13451573 | 0.77 | DRD3 (0.40) | CHRM1DRD3SLC6A9SIGMAR1 | |
| SCHEMBL1499107 | 0.76 | THRA (0.30) | — | |
| SCHEMBL23860181 | 0.76 | DRD3 (0.39) | CHRM1DRD3SLC6A9SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249145-B2 | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2016-02-02 | — | — | US | disclosed |